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Updated: Sep 24, 2025

Author Spotlight: Decoding Metastasis-to-Metastasis Seeding Using a New In Vivo Technique for Tracking Breast Cancer Spread
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血統 の 追跡 に よっ て,腫瘍 の 進化 の 構造,可塑性,経路 が 明らか に なり ます

Dian Yang1, Matthew G Jones2, Santiago Naranjo3

  • 1Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; Whitehead Institute for Biomedical Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA; David H. Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02142, USA.

Cell
|May 6, 2022
PubMed
まとめ

腫瘍の進化には 制御不能な成長につながる 遺伝的変化が含まれます この研究では ネズミの系統追跡を用いて 肺がん細胞が どのようにして 柔軟性を持ち 広がり 転移するかを明らかにしました

キーワード:
フィットネス遺伝子組み換えマウスモデル系統追跡肺がん遺伝学プラスチック性シングルセルトランスクリプトームの異質性腫瘍の進化

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VDJ-Seq: Deep Sequencing Analysis of Rearranged Immunoglobulin Heavy Chain Gene to Reveal Clonal Evolution Patterns of B Cell Lymphoma15:07

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