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Updated: Sep 24, 2025

Generalized Psychophysiological Interaction PPI Analysis of Memory Related Connectivity in Individuals at Genetic Risk for Alzheimer's Disease
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編集者訂正: 複製可能な脳全体の関連研究は数千人の個人を必要とします

Scott Marek1, Brenden Tervo-Clemmens2,3, Finnegan J Calabro4,5

  • 1Department of Psychiatry, Washington University School of Medicine, St Louis, MO, USA. smarek@wustl.edu.

Nature
|May 9, 2022
PubMed
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No abstract available in PubMed .

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
GWAS does not require the identification of the target gene involved in...
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