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Updated: Jul 23, 2026

An Assay for Quantifying Protein-RNA Binding in Bacteria
07:02

An Assay for Quantifying Protein-RNA Binding in Bacteria

Published on: June 12, 2019

アミノ酸塩基対コンタクトペアを定義する434抑制体の新しい特異性変異体

R P Wharton, M Ptashne

    Nature
    |April 6, 1987
    PubMed
    まとめ

    研究者らは,バクテリオファージ434抑制器のDNA結合特異性にとって重要な特定のアミノ酸塩基対の接触を特定した. 変異した抑制タンパク質 (Repressor [Ala 28]) は結合の変化を示し,DNAメジャー・グリューブ内の重要な相互作用を明らかにした.

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