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Updated: Sep 23, 2025

HOX Loci Focused CRISPR/sgRNA Library Screening Identifying Critical CTCF Boundaries
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OCA-T1とOCA-T2は,タフト細胞系におけるPOU2F3の共同活性化剤である

Xiaoli S Wu1,2, Xue-Yan He1, Jonathan J Ipsaro1,3

  • 1Cold Spring Harbor Laboratory, Cold Spring Harbor, NY, USA.

Nature
|May 16, 2022
PubMed
まとめ

POU2F3-OCA-T複合体は,粘膜組織と小細胞肺がんにおけるタフト細胞のアイデンティティと機能に不可欠です. この発見はタフト細胞発達の 重要なレギュラーであり 治療の標的となる可能性があります

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