関連する実験動画

Updated: Sep 23, 2025

A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target
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A Competent Hepatocyte Model Examining Hepatitis B Virus Entry through Sodium Taurocholate Cotransporting Polypeptide as a Therapeutic Target

Published on: May 10, 2022

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胆酸トランスポーターとHBV受容体NTCPの構造

Jinta Asami1, Kanako Terakado Kimura2, Yoko Fujita-Fujiharu3,4,5

  • 1Graduate School of Pharmaceutical Sciences, The University of Tokyo, Tokyo, Japan.

Nature
|May 17, 2022
PubMed
まとめ

B型肝炎ウイルス (HBV) は,宿主細胞の受容体と結合するために,大型包膜グリコタンパク質 (LHBs) を利用する. この研究は,NTCP経由でのHBV侵入の構造的基礎を明らかにし,ウイルスと宿主の相互作用を理解するための枠組みを提供します.

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