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Updated: Sep 22, 2025

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精製されたヒトタンパク質で迅速かつ効率的なDNA複製

Yasemin Baris1, Martin R G Taylor1, Valentina Aria1

  • 1MRC Laboratory of Molecular Biology, Cambridge, UK.

Nature
|May 18, 2022
PubMed
まとめ

研究者らはヒトの複製体を再構成し,DNAポリメラーゼエプシロン (Polε) がリードストランド合成の鍵であることを明らかにした. このプロセスはPCNAとCTF18-RFCを必要とし,AND-1はリードストランド複製を直接支援する.

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