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Updated: Sep 22, 2025

Method for Measuring the Activity of Deubiquitinating Enzymes in Cell Lines and Tissue Samples
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Method for Measuring the Activity of Deubiquitinating Enzymes in Cell Lines and Tissue Samples

Published on: May 10, 2015

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デウビキチナゼUSP8は,不完全な細胞分裂を促進するためにESCRT-IIIをターゲットとしています

Juliette Mathieu1, Pascale Michel-Hissier1, Virginie Boucherit1

  • 1Center for Interdisciplinary Research in Biology, Collège de France, PSL Research University, CNRS, Inserm, Paris, France.

Science (New York, N.Y.)
|May 19, 2022
PubMed
まとめ

ドロソフィラのUSP8遺伝子の喪失は生殖細胞の分裂を完了させ,過剰発現は不完全な分裂につながります. USP8によるESCRT-IIIタンパク質のユビキチン化は,この細胞分裂スイッチを調節する.

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