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Updated: Sep 22, 2025

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry
12:08

Monitoring the Reductive and Oxidative Half-Reactions of a Flavin-Dependent Monooxygenase using Stopped-Flow Spectrophotometry

Published on: March 18, 2012

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非ヘム鉄酵素がアビオロジカル・リレー C ((sp3) -H アジデーションにアクセスする方向の進化

Jinyan Rui1, Qun Zhao1, Anthony J Huls1

  • 1Department of Chemistry, Johns Hopkins University, Baltimore, MD 21218, USA.

Science (New York, N.Y.)
|May 19, 2022
PubMed
まとめ

研究者は,鉄触媒のリレーを使用して,非ヘム鉄酵素をアビオロギー的なC ((sp3) -Hアジデーションに再プログラムした. このバイオカタリシスは,高いエナティオメリック過剰とターンオーバー数を達成し,メタロ酵素触媒の開発のための新しい道を開きます.

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