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Updated: Sep 22, 2025

Visualizing Axonal Growth Cone Collapse and Early Amyloid β Effects in Cultured Mouse Neurons
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細胞内Aβ42集積は細胞発熱につながる

Chyi Wei Chung1, Amberley D Stephens1, Tasuku Konno2

  • 1Department of Chemical Engineering and Biotechnology, University of Cambridge, Philippa Fawcett Drive, Cambridge CB3 0AS, U.K.

Journal of the American Chemical Society
|May 26, 2022
PubMed
まとめ

アルツハイマー病では,アミロイドβ (Aβ42) アグリゲーションによって細胞の温度が上昇し,その上昇は阻害剤によって逆転する. この発見は潜在的にアルツハイマー病の治療法となる 新たな診断方法の開発に役立ちます

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