関連する実験動画

Updated: Sep 21, 2025

Gene Digital Circuits Based on CRISPR-Cas Systems and Anti-CRISPR Proteins
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タイプIII-EのCRISPR-Cas7-11エフェクター複合体の構造と工学

Kazuki Kato1, Wenyuan Zhou2, Sae Okazaki1

  • 1Structural Biology Division, Research Center for Advanced Science and Technology, The University of Tokyo, 4-6-1 Komaba, Meguro-ku, Tokyo 153-8904, Japan.

Cell
|June 1, 2022
PubMed
まとめ

Cas7-11 CRISPR-Casシステムは,バクテリアと哺乳類の細胞にダブルRNAターゲティング能力を提供しています. 構造的な洞察により,AAVベクトルを用いてin vivo RNAノックダウンアプリケーションのためのコンパクトなCas7-11の設計が可能になりました.

キーワード:
CRISPRについてケース7-11RNAターゲティングクリオ・エム

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