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Updated: Sep 21, 2025

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins
11:25

Targeting Cysteine Thiols for in Vitro Site-specific Glycosylation of Recombinant Proteins

Published on: October 4, 2017

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サイクロプロペノン反応剤によって活性化されるオートホーナル・N・システイン特異タンパク質の改変のためのプラットフォーム

Alena Istrate1, Michael B Geeson1, Claudio D Navo2

  • 1Yusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, CB2 1EW Cambridge, United Kingdom.

Journal of the American Chemical Society
|June 6, 2022
PubMed
まとめ

新しいサイクロプロペノン (CPO) 反応剤は,タンパク質のN端システイン残基を選択的に修正する. このタンパク質結合戦略は,精密なバイオコンジュガート製造と治療開発を可能にします.

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