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Updated: Sep 20, 2025

A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates
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A Novel Saturation Mutagenesis Approach: Single Step Characterization of Regulatory Protein Binding Sites in RNA Using Phosphorothioates

Published on: August 21, 2018

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1-デザグアノシン改変RNA:機能的なRNA原子変異の欠けている部分

Raphael Bereiter1, Eva Renard2, Kathrin Breuker1

  • 1Institute of Organic Chemistry and Center for Molecular Biosciences, University of Innsbruck, Innrain 80-82, Innsbruck 6020, Austria.

Journal of the American Chemical Society
|June 6, 2022
PubMed
まとめ

研究者は,1-デアザグアノシン (c1G) 改変RNAを合成する新しい方法を開発した. この突破は,原子変異によるRNA構造,機能,触媒の詳細な研究を可能にします.

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Site-Directed Mutagenesis for In Vitro and In Vivo Experiments Exemplified with RNA Interactions in Escherichia Coli07:04

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