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Updated: Sep 20, 2025

Visualization of HIV-1 Gag Binding to Giant Unilamellar Vesicle GUV Membranes
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Visualization of HIV-1 Gag Binding to Giant Unilamellar Vesicle GUV Membranes

Published on: July 28, 2016

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イノシトールヘキサキスファート (IP6) は,未成熟のHIV-1ガグタンパク質の組み立てを加速し,運動的に閉じ込められた形状を形成する

Alexander J Pak1, Manish Gupta1, Mark Yeager2,3,4,5

  • 1Department of Chemistry, Chicago Center for Theoretical Chemistry, Institute for Biophysical Dynamics, and James Franck Institute, The University of Chicago, Chicago, Illinois 60637, United States.

Journal of the American Chemical Society
|June 6, 2022
PubMed
まとめ

イノシトールヘキサキスファート (IP6) はHIV-1カプシドの組成を加速し,未成熟のビリオン形成を促進する. このコファクターは特定の格子欠陥を誘導し,ウイルスの形態変異とウイルスのような粒子テクノロジーを誘導する可能性があります.

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Protein Complex Assembly02:41

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Intralumenal Vesicles and Multivesicular Bodies

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