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幼児の腸内微生物群の構成は,様々なライフスタイルで大きく変化しています
Matthew R Olm1, Dylan Dahan1, Matthew M Carter1
1Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, CA, USA.
まとめ
幼児の腸内微生物の発達は ライフスタイルによって大きく異なります ハザ族の狩猟採集者の赤ちゃんは 工業国の人とは違って 独特の腸内微生物を持ち 微生物の多様性を強調しています
科学分野:
- 微生物学
- 人間 生態系
- ゲノミクス
背景:
- 幼児の微生物群の組み立ては 工業化された集団でよく研究されています
- 工業化されていない地域における幼児の微生物群に関するデータは限られている.
研究 の 目的:
- 工業化されていない集団 (Hadza) の乳児の微生物群の発達を調査する.
- ライフスタイルの要因を考慮して 幼児の微生物群を比較する
主な方法:
- ハザ族の狩猟採集者の 乳児の便のサンプルを 精査したところ
- 幼児の微生物群のデータを分析したものです
主要な成果:
- ハザの幼児の微生物は 独特の軌跡を示し 新しい種を産み出します
- 工業化された乳児は *Bifidobacterium infantis* が少なく,母乳の利用遺伝子が少ない.
- 菌株はハザ族の母子二重体の中で共有されていて 遺伝性を示しています
結論:
- 幼児の微生物群の構成は 集団特有のライフスタイルによって形成されます
- グローバル・マイクロバイオームの研究には 多様で工業化されていない集団が含まれなければなりません
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