ヒトの新型コロナウイルスの構造,受容体認識,抗原性 CCoV-HuPn-2018 スパイクグリコタンパク質

M Alejandra Tortorici1, Alexandra C Walls2, Anshu Joshi1

  • 1Department of Biochemistry, University of Washington, Seattle, WA 98195, USA.

Cell
|June 14, 2022
PubMed
まとめ

新型犬型コロナウイルス (CCoV-HuPn-2018) がヒトで発見され,種間感染が増加していることが明らかになった. 研究者はそのスパイクタンパク質の構造を明らかにし,そのエントリー受容体としてアミノペプチダゼN (APN) を特定し,治療開発の道を開いた.

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