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Updated: Sep 8, 2025

Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods
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Characterize Disease-related Mutants of RAF Family Kinases by Using a Set of Practical and Feasible Methods

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アンドロゲン受容体阻害は,BRAF/MEK標的治療に対する反応を促進する

Christopher P Vellano1, Michael G White2, Miles C Andrews2,3

  • 1TRACTION Platform, Therapeutics Discovery Division, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Nature
|June 15, 2022
PubMed
まとめ

メラノーマの女性患者は,男性と比較して,BRAF/ MEK標的治療に有意に優れた反応を示した. アンドロゲン受容体経路を標的にすることで,両方の性別で治療効果が向上する可能性があります.

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