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Updated: Sep 7, 2025

Constructing Cyclic Peptides Using an On-Tether Sulfonium Center
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Constructing Cyclic Peptides Using an On-Tether Sulfonium Center

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双サイト認識経路による多種多様なピリジン基マクロサイクルペプチドへのアクセス

Dinh T Nguyen1,2,3, Tung T Le1,3, Andrew J Rice1,2

  • 1Department of Chemistry, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, United States.

Journal of the American Chemical Society
|June 17, 2022
PubMed
まとめ

研究者は,線形前駆体からピリジンベースのマクロサイクルペプチド (ピリチド) を合成するための新しい酵素方法を開発した. このアプローチにより,薬物の発見のための多様なピリチド類の作成が可能になり,これらの貴重な分子構造へのアクセスを拡大します.

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