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Updated: Sep 7, 2025

Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric AnalysisMechanisms
09:41

Preparation of Single-Cell Suspension of Mouse Thymic Epithelial Cells and Staining of Intracellular Molecules for Flow Cytometric AnalysisMechanisms

Published on: July 26, 2024

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甲状腺上皮細胞は,自己反応性T細胞を排除するために,系統を決定する転写因子を共用する

Daniel A Michelson1, Koji Hase2, Tsuneyasu Kaisho3

  • 1Department of Immunology, Harvard Medical School, Boston, MA 02115, USA.

Cell
|June 17, 2022
PubMed
まとめ

骨髄上皮細胞 (mTEC) は,系統を定義する転写因子を用いて特殊な"模倣性"の細胞を作ります. これらの細胞は,自己耐性を確立し,自己免疫を防ぐために重要な周辺組織抗原 (PTAs) を発現します.

キーワード:
エアーT細胞トレグ自己免疫性mTEC についてマイクロフォールドミメティック・セルトイマストレランス転写因子

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