関連する実験動画

Updated: Sep 6, 2025

iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution
10:45

iCLIP - Transcriptome-wide Mapping of Protein-RNA Interactions with Individual Nucleotide Resolution

Published on: April 30, 2011

58.6K

細胞内の小分子RNA結合部位のトランスクリプトーム幅のマッピングは,イソフォーム特異的な退化因子である

Yuquan Tong1, Quentin M R Gibaut1, Warren Rouse2

  • 1Department of Chemistry, The Scripps Research Institute, Jupiter, Florida 33458, United States.

Journal of the American Chemical Society
|June 23, 2022
PubMed
まとめ

研究者は,キエスチン硫酸酸化酵素1型a (QSOX1-a) mRNAを標的にして,RNAに特異的に結合する新しい小分子,F1を特定した. この発見により,がん治療のための標的型RNA分解システムの開発が可能になった.

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