関連する実験動画

Updated: Sep 6, 2025

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation
12:49

Human Peripheral Blood Neutrophil Isolation for Interrogating the Parkinson's Associated LRRK2 Kinase Pathway by Assessing Rab10 Phosphorylation

Published on: March 21, 2020

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パーキンソン病のリスクタンパク質TMEM175は,リソソーム内の陽子活性化陽子チャンネルである

Meiqin Hu1, Ping Li1, Ce Wang2

  • 1Department of Molecular, Cellular, and Developmental Biology, University of Michigan, 4114 Biological Sciences Building (BSB), 1105 N. University Ave, Ann Arbor, MI 48109, USA; Collaborative Innovation Center of Yangtze River Delta Region Green Pharmaceuticals, College of Pharmaceutical Sciences, Zhejiang University of Technology, Hangzhou 310014, China.

Cell
|June 24, 2022
PubMed
まとめ

TMEM175はリン酸体内の陽子チャンネルとして作用し,その酸度を調節する. このタンパク質は

キーワード:
プロトンチャンネル酸性化劣化するリソソームpH最適値

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Rab10 Phosphorylation Detection by LRRK2 Activity Using SDS-PAGE with a Phosphate-binding Tag08:55

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