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Updated: Sep 6, 2025

Isolation and Identification of Extravascular Immune Cells of the Heart
08:24

Isolation and Identification of Extravascular Immune Cells of the Heart

Published on: August 23, 2018

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チェックポイント阻害剤誘発性心筋炎に関連する病原性免疫細胞サブセットの特定

Han Zhu1,2,3, Francisco X Galdos2,4, Daniel Lee2

  • 1Department of Medicine (H.Z., S.W., J.W.N., H.A.W., S.A.R., S.S., R.M.W., P.K.N., S.M.W.), Stanford University, CA.

Circulation
|June 28, 2022
PubMed
まとめ

免疫チェックポイント阻害剤 (ICI) 治療は心筋炎を引き起こす可能性があります. この研究では,CD45RA (Temra CD8+ 細胞) を再発するクローン細胞性細胞性Tエフェクター記憶細胞が,ICI 筋硬化症の主要な誘発因子として特定され,潜在的な診断および治療標的となる.

キーワード:
免疫チェックポイント阻害剤免疫フェノタイプ決定免疫療法心筋炎単細胞分析

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