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Updated: Sep 6, 2025

RNAi Interference by dsRNA Injection into Drosophila Embryos
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Published on: April 11, 2011

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Drosophila Dicer-2-Loqs-PDによるdsRNA処理に関する構造的洞察

Shichen Su1, Jia Wang2, Ting Deng1

  • 1State Key Laboratory of Genetic Engineering, Collaborative Innovation Center of Genetics and Development, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.

Nature
|June 29, 2022
PubMed
まとめ

この研究では,Dicer- 2 (Dcr- 2) とLoquacious- PD (Loqs- PD) が二重鎖RNA (dsRNA) を小さな干渉RNA (siRNA) に処理する方法を明らかにした. 構造的な洞察は,siRNAの産生を促すATP依存の構造変化を示しています.

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