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Updated: Sep 6, 2025

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神経学的疾患に関連した変異は,低複雑性のタンパク質配列の自己結合を強化する

Xiaoming Zhou1, Lily Sumrow1, Kyuto Tashiro1

  • 1Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Science (New York, N.Y.)
|June 30, 2022
PubMed
まとめ

低複雑性ドメイン (LCD) のタンパク質は,ダイナミックな細胞構造を形成することができる. 神経退行性疾患に関連した変異は,これらの構造の安定性を高め,細胞組織に影響します.

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