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Updated: Sep 6, 2025

Real Time Measurements of Membrane Protein:Receptor Interactions Using Surface Plasmon Resonance SPR
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マルチドラッグABCトランスポーターBmrAにおける非対称なATP水解を固体NMRで検出

Denis Lacabanne1, Thomas Wiegand1, Margot Di Cesare2

  • 1Physical Chemistry, ETH Zurich, 8093 Zurich, Switzerland.

Journal of the American Chemical Society
|July 1, 2022
PubMed
まとめ

この研究は,ABCトランスポーターでATPの水解がどのように起こるかを明らかにしています. 固体 NMR を用いて 研究者たちは ATP 結合部位が水解の間に対称性を失い その過程の後には 回復することを発見しました

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