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Updated: Sep 5, 2025

Identification and Classification of Position-specific GABAA Receptor Subunit Missense Variants for Their Role In Hippocampal Pyramidal Neurons
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Published on: June 6, 2025

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GABAA受容体の自己免疫性脳炎の構造的メカニズム

Colleen M Noviello1, Jakob Kreye2, Jinfeng Teng1

  • 1Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell
|July 8, 2022
PubMed
まとめ

脳炎を引き起こす自己抗体は構造的に分析され,GABA-A受容体を直接抑制することを明らかにしました. これらの抗体はどのように神経伝達を妨害し,重度の神経学的症状を引き起こすかを説明します.

キーワード:
サイズループ受容体GABA (A) 受容体について自己免疫疾患クリオ電子顕微鏡脳炎

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