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Updated: Sep 5, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
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現在流通しているオミクロンSARS-CoV-2サブ変種BA.2およびBA.1.1に対するヒトACE2の高結合 afinityの構造的基礎

Linjie Li1, Hanyi Liao1, Yumin Meng1

  • 1CAS Key Laboratory of Pathogen Microbiology and Immunology, Institute of Microbiology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China.

Cell
|July 9, 2022
PubMed
まとめ

SARS-CoV-2のオミクロンサブ変種は,多数の変異を示しています. BA.1.1 と BA.2 は,受容体結合ドメイン (RBD) の特定の変異により,BA.1 と BA.3 よりも高いヒト血管新生変換酵素2 (hACE2) の結合親和性を示しています.

キーワード:
オミクロンRBD についてSARS-CoV-2についてハエCE2

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