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Updated: Sep 4, 2025

High-Resolution Complexome Profiling by Cryoslicing BN-MS Analysis
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SHOC2-MRAS-PP1Cホロフォスファタゼ複合体の構造機能分析

Jason J Kwon1,2,3, Behnoush Hajian4, Yuemin Bian4

  • 1Cancer Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA.

Nature
|July 13, 2022
PubMed
まとめ

SHOC2-MRAS-PP1C複合体は細胞のシグナル伝達を制御する. 研究者はその構造を決定し,RASopathiesの変異がどのようにその活動を強化し,がん治療の開発の洞察を提供することを明らかにしました.

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