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広く中和する抗体は,コロナウイルスの融合ペプチドを標的とする

Cherrelle Dacon1, Courtney Tucker1,2, Linghang Peng3

  • 1Antibody Biology Unit, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD 20852, USA.

Science (New York, N.Y.)
|July 20, 2022
PubMed
まとめ

研究者は,SARS-CoV-2の変種を含むすべてのヒトコロナウイルスの融合ペプチドを標的とした6つの抗体を特定した. 1つの抗体であるCOV44-79は,ハムスターのモデルで疾患の重症性を低下させ,ワクチン標的として融合ペプチドを示唆した.

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