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関連する概念動画

Development of the Heart01:27

Development of the Heart

1.2K
The development of the human heart, a crucial organ, commences from the mesoderm on the 18th or 19th day after fertilization. This process initiates in the cardiogenic area, a group of mesodermal cells at the embryo's head end, which evolves into elongated strands known as cardiogenic cords. These cords undergo a transformation to form hollow-centered endocardial tubes.
As the embryo undergoes lateral folding, these paired tubes approach each other, merging into a single primitive heart...
1.2K
Layers of the Heart Wall01:15

Layers of the Heart Wall

3.2K
The heart wall comprises three distinct layers: the epicardium, myocardium, and endocardium. The outermost layer, the epicardium, is the visceral layer of the serous pericardium, featuring a thin, transparent mesothelial surface and an inner layer of areolar connective tissue with fat deposits that increase with age.
The myocardium, the thickest layer, consists of cardiac muscle cells interconnected by intercalated discs and crisscrossing connective tissue fibers. These muscle fibers contract...
3.2K
Chambers of the Heart01:16

Chambers of the Heart

5.8K
The human heart is a complex organ made up of four chambers: the right and left atria and the right and left ventricles. These internal chambers are separated by partitions known as the interatrial and interventricular septa. The exterior of the heart features a groove known as the coronary sulcus that demarcates the atria from the ventricles, while the anterior and posterior interventricular sulci distinguish between the two ventricles.
Deoxygenated blood from the body is received in the right...
5.8K
Heart Valves01:16

Heart Valves

5.6K
The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
5.6K
Anatomy of the Heart01:27

Anatomy of the Heart

110.3K
The human heart is made up of three layers of tissue that are surrounded by the pericardium, a membrane that protects and confines the heart. The outermost layer, closest to the pericardium, is the epicardium. The pericardial cavity separates the pericardium from the epicardium. Beneath the epicardium is the myocardium, the middle layer, and the endocardium, the innermost layer. There are four chambers of the heart: the right atrium, the right ventricle, the left atrium, and the left ventricle.
110.3K
Overview of the Heart01:07

Overview of the Heart

7.0K
The heart, a muscular organ located in the chest, functions as the body's pump, circulating blood through the vascular system. It has four chambers: two atria on top and two ventricles below. The right atrium receives deoxygenated blood from the body and passes it to the right ventricle, which pumps it to the lungs for oxygenation. The left atrium receives oxygenated blood from the lungs and transfers it to the left ventricle, which pumps it to the rest of the body.
The heart's structure...
7.0K

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Semi-automated Optical Heartbeat Analysis of Small Hearts
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Semi-automated Optical Heartbeat Analysis of Small Hearts

Published on: September 16, 2009

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デザインによるハート

Michael V Sefton1, Craig A Simmons2

  • 1Medicine by Design, Institute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.

Science (New York, N.Y.)
|July 20, 2022
PubMed
まとめ
この要約は機械生成です。

臓器を大幅に改善する 拡張性のある螺旋状の心臓組織パターンをバイオファブリックしました

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Visualizing the Beating Heart in Drosophila
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関連する実験動画

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科学分野:

  • 生物医学工学
  • 再生医療
  • 心血管科学

背景:

  • 心臓病は 世界中で主要な死因です
  • 心不全の治療には 限界があります
  • バイオファブリケーションは 心臓組織工学の有望な道を示しています

研究 の 目的:

  • 螺旋状の心臓組織を 生体的に製造する 拡張可能な方法を開発する
  • この螺旋構造が心臓のポンプ機能を 強化するかどうかを調べるため

主な方法:

  • 先進的なバイオファブリケーション技術を使って 心臓組織を組み立てました
  • 組織構造の中で 特殊な螺旋状のパターンを設計した
  • バイオファブリック組織の収縮とポンプ能力を評価した.

主要な成果:

  • 心臓組織のスケーラブルな生産が成功しました. 定義された螺旋的なパターンです.
  • 螺旋組織構造のポンプ効率は,非螺旋制御と比較して大幅に増加しています.
  • 組織化された細胞の収縮と 組織化された細胞の収縮を示した

結論:

  • 心臓組織のスケーラブルなバイオファブリケーションは可能である.
  • 心臓のポンプ機能を高めるには 螺旋状のパターンが重要です
  • このアプローチは 改善された心臓療法を開発する可能性を秘めています