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Issues And Trends In Healthcare Delivery System01:29

Issues And Trends In Healthcare Delivery System

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The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
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Genomic DNA in Eukaryotes00:58

Genomic DNA in Eukaryotes

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Eukaryotes have large genomes compared to prokaryotes. To fit their genomes into a cell, eukaryotic DNA is packaged extraordinarily tightly inside the nucleus. To achieve this, DNA is tightly wound around proteins called histones, which are packaged into nucleosomes that are joined by linker DNA and coil into chromatin fibers. Additional fibrous proteins further compact the chromatin, which is recognizable as chromosomes during certain phases of cell division.
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Genomics02:02

Genomics

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Genomics is the science of genomes: it is the study of all the genetic material of an organism. In humans, the genome consists of information carried in 23 pairs of chromosomes in the nucleus, as well as mitochondrial DNA. In genomics, both coding and non-coding DNA is sequenced and analyzed. Genomics allows a better understanding of all living things, their evolution, and their diversity. It has a myriad of uses: for example, to build phylogenetic trees, to improve productivity and...
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Genome-wide Association Studies-GWAS01:11

Genome-wide Association Studies-GWAS

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Genome-wide association studies or GWAS are used to identify whether common SNPs are associated with certain diseases. Suppose specific SNPs are more frequently observed in individuals with a particular disease than those without the disease. In that case, those SNPs are said to be associated with the disease. Chi-square analysis is performed to check the probability of the allele likely to be associated with the disease.
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Genomic DNA in Prokaryotes00:46

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The genome of most prokaryotic organisms consists of double-stranded DNA organized into one circular chromosome in a region of cytoplasm called the nucleoid. The chromosome is tightly wound, or supercoiled, for efficient storage. Prokaryotes also contain other circular pieces of DNA called plasmids. These plasmids are smaller than the chromosome and often carry genes that confer adaptive functions, such as antibiotic resistance.
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Although bacterial genomes are much...
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DNA as a Genetic Template02:05

DNA as a Genetic Template

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ゲノムデータのためのブロックチェーン対応の先住民データ主権の枠組みの確立

Tim K Mackey1, Alec J Calac2, B S Chenna Keshava3

  • 1Global Health Program, Department of Anthropology, University of California, San Diego, San Diego, CA, USA; S-3 Research LLC, San Diego, CA, USA; Global Health Policy and Data Institute, San Diego, CA, USA; BlockLAB, San Diego Supercomputer Center, San Diego, CA, USA.

Cell
|July 22, 2022
PubMed
まとめ

新しいブロックチェーンフレームワークは,倫理的な健康ゲノミクスのために先住民族のデータ主権を優先します. このアプローチは 疎外されたコミュニティが 価値あるゲノムデータを管理し 技術のギャップを埋めることを保証します

キーワード:
ブロックチェーン分散台帳技術についてゲノム学健康に関する公平性インディジェンス・ヘルス

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科学分野:

  • ゲノミクス
  • データサイエンス
  • 原住民の研究

背景:

  • 健康とゲノムデータ生成の 急速な進歩です
  • 既存の技術は 疎外されたコミュニティの 価値観や優先順位を無視しています
  • コミュニティのニーズに沿ったデータフレームワークの必要性

研究 の 目的:

  • ブロックチェーンのゲノミクスのデータフレームワークを概念化する
  • ゲノムデータの管理に先住民族のデータ主権の原則を統合する.
  • 倫理的でコミュニティ中心のアプローチを提案する

主な方法:

  • 概念的枠組みの開発
  • ブロックチェーン技術と先住民族のデータ主権に関する文献レビュー
  • ゲノムデータの実践における現在のギャップの分析

主要な成果:

  • 提案されたブロックチェーンゲノミクスのデータフレームワークが概念化されています.
  • この枠組みは"先住民族のデータ主権"の原則に基づいています
  • 強化されたデータセキュリティ,制御,倫理的なガバナンスの可能性

結論:

  • ブロックチェーンの技術は,ゲノミクスにおける先住民族のデータ主権を実装するための実行可能な解決策を提供します.
  • この枠組みにより 疎外されたコミュニティが 医療データを管理できるようになります
  • 将来の作業は,このフレームワークを現実世界のアプリケーションで開発し,テストすることに重点を置くべきです.