関連する実験動画

Updated: Sep 3, 2025

A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses
06:32

A Galleria mellonella Oral Administration Model to Study Commensal-Induced Innate Immune Responses

Published on: March 21, 2019

8.2K

アッケルマンシア・ムチニフィラ・フォスフォリピッドは,ホメオスタティックな免疫反応を誘発する

Munhyung Bae1,2, Chelsi D Cassilly1, Xiaoxi Liu1,3

  • 1Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Blavatnik Institute, Boston, MA, USA.

Nature
|July 27, 2022
PubMed
まとめ

研究者らは腸内細菌である Akkermansia muciniphila の特定の脂質を特定し,その免疫強化効果を模倣した. この分子は独特のトール型受容体 (TLR2-TLR1) 経路を通じて信号を送り込み,腸内微生物群の洞察力を提供します.

さらに関連する動画

A Novel Method for the Culture and Polarized Stimulation of Human Intestinal Mucosa Explants06:38

A Novel Method for the Culture and Polarized Stimulation of Human Intestinal Mucosa Explants

Published on: May 1, 2013

13.2K
Harvesting Murine Alveolar Macrophages and Evaluating Cellular Activation Induced by Polyanhydride Nanoparticles11:26

Harvesting Murine Alveolar Macrophages and Evaluating Cellular Activation Induced by Polyanhydride Nanoparticles

Published on: June 8, 2012

19.9K

関連する概念動画

Defense Mechanism Against Infection01:26

Defense Mechanism Against Infection

Natural flora, body system defenses, and inflammation are natural barriers of the body against infectious agents regardless of previous exposure. Normal floras of the human body refer to the microbial population that colonizes the skin and mucous membranes.
In addition, many body organ systems have unique defenses against infection. The skin is an intact, multilayered surface preventing invasion by microorganisms unless impaired. Mucous membranes lining the mouth, nose, and eyelids are barriers...
7.2K
Surface Membrane Barriers01:18

Surface Membrane Barriers

The skin and mucous membranes serve as the primary line of defense against pathogens by providing both physical and chemical protection. These barriers are essential in preventing the entry and establishment of microbes, thereby maintaining the integrity of the host.
The outer layer of the skin, the epidermis, is a robust barrier comprising layers of closely packed keratinized cells. This dense arrangement prevents microbes from penetrating the body. The periodic shedding of epidermal cells...
1.4K
Defense Against Bacterial Pathogens01:31

Defense Against Bacterial Pathogens

The human immune system is a complex network of cells, tissues, and organs that work together to defend the body against bacterial infections. It consists of various immune cells, each playing a specific role in the defense mechanism.
Phagocytes
Phagocytes are the frontline soldiers of the immune system. They include neutrophils and macrophages. Neutrophils are the most abundant type of white blood cell and are quickly mobilized to the site of infection. Macrophages are larger cells that patrol...
1.5K
Cell-mediated Immune Responses01:40

Cell-mediated Immune Responses

Overview
71.0K
Antigens Involved in Adaptive Immunity01:26

Antigens Involved in Adaptive Immunity

An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and...
648
Immune Response Against Viral Pathogens01:29

Immune Response Against Viral Pathogens

The immune system's response to viral infections is a complex and coordinated process involving natural killer (NK) cells, T cell-mediated responses, and antibody-mediated responses.
NK Cells
NK cells are a crucial part of our innate immune system, acting as the first line of defense against viral infections. These cells can recognize and kill infected cells without prior exposure to the virus, effectively slowing down the spread of infection. Additionally, NK cells produce proinflammatory...
909