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Updated: Sep 3, 2025

Quantification of Coenzyme A in Cells and Tissues
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PI3KはビタミンB5からコエンザイムAの新合成を誘導する

Christian C Dibble1, Samuel A Barritt2, Grace E Perry2

  • 1Department of Pathology, Cancer Research Institute, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. ccdibble@bidmc.harvard.edu.

Nature
|July 27, 2022
PubMed
まとめ

フォスフォノシチド3キナーゼ (PI3K) 信号は,CoAの産生抑制体であるPANK4をリン酸化することによって,コエンザイムA (CoA) の合成を活性化します. この経路は,成長因子と癌に対する反応として,脂質代謝と細胞成長を調節する.

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