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Updated: Sep 3, 2025

Synthesis of Masarimycin, a Small Molecule Inhibitor of Gram-Positive Bacterial Growth
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ダロバクチンAの総合成

Marko Nesic1, David B Ryffel1, Jonathan Maturano1

  • 1Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois at Urbana-Champaign, Urbana, Illinois61801, United States.

Journal of the American Chemical Society
|July 28, 2022
PubMed
まとめ

研究者は,グラム陰性細菌を標的とした新しい抗生物質であるドロバクチンAの完全な合成を達成しました. この効率的な合成は,非正規のアミノ酸のスケーラブルな経路とビスマクロサイクルのための連続的なラロック・インドルサイクルを使用した.

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