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Updated: Sep 3, 2025

Single-Molecule Fluorescence Visualization of DNA Polymerase Dynamics at G-Quadruplexes
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ポリメラーゼ ηは,グアニン四重複構造の複製を促進するためにDHX9ヘリカーゼを勧誘する

Feng Tang1, Yinan Wang1, Zi Gao1

  • 1Department of Chemistry, University of California, Riverside, California 92521-0403, United States.

Journal of the American Chemical Society
|July 29, 2022
PubMed
まとめ

DNAポリメラーゼエタ (Pol η) は,ヘリコラーゼDHX9と相互作用して,難しいグアニン四重体 (G4) 構造の間のDNA複製を促進します. この相互作用は 複製の過程で DNAの異常な構造を回避するために 極めて重要です

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