関連する実験動画

Updated: Sep 3, 2025

Real-Time Measurement of the Mitochondrial Bioenergetic Profile of Neutrophils
09:39

Real-Time Measurement of the Mitochondrial Bioenergetic Profile of Neutrophils

Published on: June 2, 2023

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ミトコンドリアのROSはガスダーミンD媒介性死滅によって感染感を高めます

Chi G Weindel1, Eduardo L Martinez1, Xiao Zhao2

  • 1Department of Microbial Pathogenesis and Immunology, Texas A&M Health, College of Medicine, Bryan, TX 77807, USA.

Cell
|July 30, 2022
PubMed
まとめ

変異したLRRK2はミトコンドリアの機能を破壊し,マクロファージがネクロプトーシスに切り替わります. これは,Mycobacterium tuberculosis感染に対する反応として,高炎症と重度の病理に繋がります.

キーワード:
ドロソフィラ・メラノガスターLRRK2ミコバクテリア 結核パーキンソン病RIPK3 について免疫代謝炎症ゾーム炎症生まれつきの免疫ピロプトーシス

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