関連する実験動画

Updated: Sep 3, 2025

Author Spotlight: Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos
12:35

Author Spotlight: Optogenetic Inhibition of Rho1-Mediated Actomyosin Contractility Coupled with Measurement of Epithelial Tension in Drosophila Embryos

Published on: April 14, 2023

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ガストルレーション中のTETタンパク質の内在的および外在的効果

Saifeng Cheng1, Markus Mittnenzweig2, Yoav Mayshar1

  • 1Department of Molecular Cell Biology, Weizmann Institute of Science, 7610001 Rehovot, Israel.

Cell
|July 31, 2022
PubMed
まとめ

10−11 転位 (TET) 遺伝子の喪失は胚の死亡を引き起こす. TET欠乏細胞は野生型胚内で分化できますが,突然変異した胚だけが早期発育に失敗し,細胞自律のTET機能を明らかにします.

キーワード:
DNA脱メチル化細胞の運命を決める発達生物学エピジェネティクスゲノム編集マウスガストルレーション単細胞ゲノム幹細胞

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