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Updated: Sep 2, 2025

From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028
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From a Natural Product to Its Biosynthetic Gene Cluster: A Demonstration Using Polyketomycin from Streptomyces diastatochromogenes Tü6028

Published on: January 13, 2017

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ポリケチド抗生物質の生物合成における酵素触媒によるスピロアセタル形成

Oksana Bilyk1, Gabriel S Oliveira2, Rafaela M de Angelo3

  • 1Department of Biochemistry, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, United Kingdom.

Journal of the American Chemical Society
|August 3, 2022
PubMed
まとめ

研究者らは,ポリケチド生物合成におけるスピロケタル形成に不可欠な新種のスピロケタルサイクラス酵素を発見した. この酵素はオサミシンとオリゴミシンを生成するために不可欠であり,その構造と触媒機構は現在解明されています.

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