関連する実験動画

Updated: Sep 2, 2025

Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies
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Investigating Target Gene Function in a CD40 Agonistic Antibody-induced Colitis Model using CRISPR/Cas9-based Technologies

Published on: June 2, 2021

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RNA編集は,一般的な炎症性疾患の遺伝的リスクの根底にある

Qin Li1, Michael J Gloudemans2,3, Jonathan M Geisinger1

  • 1Department of Genetics, Stanford University, Stanford, CA, USA.

Nature
|August 3, 2022
PubMed
まとめ

ADARによるRNA編集は免疫反応と炎症を抑制する. 炎症性疾患に関連した遺伝子変異は RNA編集を減らし 免疫経路を活性化します これは一般的な炎症性疾患における 重要なメカニズムとして RNA編集を強調しています

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CRISPR Gene Editing Tool for MicroRNA Cluster Network Analysis

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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry

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