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Updated: Sep 2, 2025

Inner Mitochondrial Membrane Sensitivity to Na+ Reveals Partially Segmented Functional CoQ Pools
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単一残留物K12は,ミトコンドリアの電圧依存アニオンチャネルゲートの例外的な電圧感受性を支配する

Van A Ngo1,2, María Queralt-Martín3,4, Farha Khan5

  • 1Center for Molecular Simulations, Department of Biological Sciences, University of Calgary, Calgary, AB T2N 1N4, Canada.

Journal of the American Chemical Society
|August 4, 2022
PubMed
まとめ

電圧依存アニオンチャネル (VDAC) の単一の残留物K12が電圧感受性を制御する. ミトコンドリア機能に不可欠なVDACゲーティングは,K12運動の影響を受けたβバレルの変動によって引き起こされます.

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