冠動脈疾患の患者の管理における通常の圧力線評価と従来の血管検査: RIPCORD 2 試験
Rodney H Stables1, Liam J Mullen1, Mostafa Elguindy1
1Liverpool Heart & Chest Hospital, UK (R.H.S., L.J.M., M.E., Y.H.A.-E., I.K.).
Circulation
|August 10, 2022
まとめ
冠動脈血管撮影中の系統的断片流量準備 (FFR) 評価は,安定した胸痛または心筋梗塞の患者で,血管撮影単独と比較して,費用を削減したり,生活の質を向上させなかった.
科学分野:
- 心臓病科
- 介入心臓科
- 健康 経済
背景:
- 断片流量リザーブ (FFR) 測定ガイド 皮膚経冠動脈介入
- この研究では,診断用冠動脈動脈造影におけるFFRの体系的な評価が,リソースの利用と生活の質を改善するかどうかを調査した.
研究 の 目的:
- 冠動脈疾患の管理において,体系的なFFRによる評価と血管検査のみの効果を比較する.
主な方法:
- イギリスの17のセンターで1100人の患者を対象としたオープンなランダム化比較試験です.
- 患者さんは血管検査のみか,系統的な圧力線検査 (血管検査+FFR) による血管検査を受けた.
- 1年後のコプライマリーアウトカムは,国立保健局の病院費用と生活の質でした.
主要な成果:
- 病院費用の平均は血管検査 (4136ポンド) と血管検査+FFR (4510ポンド) の間ではP=0.137であった.
- 生活の質 (EuroQol EQ- 5D- 5L ビジュアルアナログスケール) で有意な差は認められなかった (75対75,P=0. 88).
- 複合的階層的な事件率は,血管図とFFRで9. 5% (P=0. 64) であった.
結論:
- FFRの体系的な評価は,医療費の大幅な削減につながらなかった.
- この戦略は,血管検査のみと比較して,患者の生活の質の改善を示さなかった.
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