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Updated: Sep 2, 2025

Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist
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Spatial and Temporal Control of T Cell Activation Using a Photoactivatable Agonist

Published on: April 25, 2018

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サイクルヌクレオチド誘発の螺旋構造はTIR免疫エフェクタを活性化させる

Gaëlle Hogrel1, Abbie Guild2,3, Shirley Graham1

  • 1School of Biology, University of St Andrews, St Andrews, UK.

Nature
|August 10, 2022
PubMed
まとめ

この研究は 細菌の抗ウイルスシステムが 循環型核酸を使って 防御機構を組み立てる方法を示しています このサイクル型トライアデニラートは分子接着剤として作用し,Toll/インタールイキン-1受容体 (TIR) 酵素を活性化し,NAD+を分解し,感染と戦う.

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