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Updated: Sep 1, 2025

Xenopus laevis as a Model to Identify Translation Impairment
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Xenopus laevis as a Model to Identify Translation Impairment

Published on: September 27, 2015

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FXR1のLLPSは,蓄積されたmRNAの翻訳を活性化することによって精子生成を誘導する

Jun-Yan Kang1, Ze Wen1, Duo Pan1

  • 1State Key Laboratory of Molecular Biology, State Key Laboratory of Cell Biology, Shanghai Key Laboratory of Molecular Andrology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.

Science (New York, N.Y.)
|August 11, 2022
PubMed
まとめ

脆弱なX関連 (FXR) タンパク質1は精子の発達における遺伝子活性化を誘導する. このRNA結合タンパク質は,蓄積されたメッセンジャーRNAを活性化するために液体-液体相分離を使用し,適切な精子の形成と男性の生育性を確保します.

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