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Updated: Sep 1, 2025

Detection of Ligand-activated G Protein-coupled Receptor Internalization by Confocal Microscopy
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細胞内化におけるアトロピソメリスムの重要な役割を解明する

Claire Donohoe1,2, Fábio A Schaberle1, Fábio M S Rodrigues1

  • 1CQC, Coimbra Chemistry Center, University of Coimbra, Rua Larga, Coimbra 3004-535, Portugal.

Journal of the American Chemical Society
|August 12, 2022
PubMed
まとめ

単一の結合の回転により,細胞の吸収と治療効果を高める薬剤アトロピソーマが生成されます. レダポルフィンのα4アトロピゾーマーには,優れた細胞浸透性と光力学療法反応が示されています.

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