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Updated: Sep 1, 2025

Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice
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Tumor Transplantation for Assessing the Dynamics of Tumor-Infiltrating CD8+ T Cells in Mice

Published on: June 12, 2021

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MYBは,チェックポイント阻害に対するT細胞の疲労と反応を指揮する

Carlson Tsui1, Lorenz Kretschmer2, Svenja Rapelius2

  • 1Department of Microbiology and Immunology, The Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria, Australia.

Nature
|August 17, 2022
PubMed
まとめ

慢性感染症と闘うのに不可欠なCD8+ T細胞は,幹細胞のようなCD62L+ T前駆体 (TPEX) 細胞によって維持されます. 転写因子MYBは免疫療法に対する機能と反応の鍵です.

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