米国成人の脂質濃度と脂質コントロールの傾向,2007年−2018年
Rahul Aggarwal1,2, Deepak L Bhatt2, Fatima Rodriguez3
1Richard A. and Susan F. Smith Center for Outcomes Research, Beth Israel Deaconess Medical Center and Harvard Medical School, Boston, Massachusetts.
JAMA
|August 23, 2022
まとめ
アメリカでは,2007年から2018年の間に脂質濃度が改善したが,スタチン療法を受けた患者の脂質コントロール率は停滞した. 性別や人種/民族の差は残った.
科学分野:
- 心血管の健康
- 公衆衛生
- 流行病学について
背景:
- 高い脂質濃度は,心血管疾患の有意で修正可能な危険因子です.
- 人口レベルでの脂質の傾向と制御を理解することは公衆衛生の取り組みにとって極めて重要です.
研究 の 目的:
- 2007年から2018年までの米国成人の脂質濃度と対照率の動向を分析する.
- これらの傾向が性別や人種/民族によって変化しているかどうかを調査する.
主な方法:
- 全米保健栄養調査 (2007年−2018年) の全国的に代表的な米国成人の33,040人の連続的横断分析.
- 脂質濃度と脂質コントロール (総コレステロール ≤200 mg/ dL) を評価した.
主要な成果:
- 年齢調整した総コレステロールは全体的に197 mg/dLから189 mg/dL (2007年−2018年) に大幅に改善した.
- スタチン使用者の脂質コントロール率は有意な変化を示さなかった (78. 5%から79. 5%),改善はメキシコ系アメリカ人のみに見られた.
- 女性,黒人,その他のヒスパニック系成人の割合は白人成人に比べて低い.
結論:
- 脂質濃度が2007年から2018年の間に改善され,ほとんどの人種および民族集団は進歩を示しました.
- ステチン使用者の脂質コントロール率は著しく改善されず,継続的な格差に対処するための標的型介入の必要性を強調した.
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