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Updated: Aug 31, 2025

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids
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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

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選択的非自然な塩基配列とDNA中の2−ヒドロキシ−2−デオキシアデノシンの認識

Ryo Miyahara1, Yosuke Taniguchi1

  • 1Graduate School of Pharmaceutical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka 812-8582, Japan.

Journal of the American Chemical Society
|August 24, 2022
PubMed
まとめ

研究者はDNAナノテクノロジーと診断において,2-ヒドロキシ-2'-デオキシアデノシン (2-OH-dA) との安定的かつ選択的な非自然な塩基ペアリングのために,新種の人工核酸,擬似-dC (ψdC) を開発した.

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