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異なるゲノム経路は 動物と真菌の起源より先にある
Eduard Ocaña-Pallarès1,2, Tom A Williams3, David López-Escardó4,5
1Institut de Biologia Evolutiva (CSIC-Universitat Pompeu Fabra), Barcelona, Spain. ed3716@gmail.com.
Nature
|August 24, 2022
まとめ
動物と真菌は共通の祖先であるオピストホコンタから 異なる遺伝的経路で進化した. 動物の起源は多細胞性のための遺伝子獲得を含み,真菌は遺伝子損失を見て代謝機能を保持しました.
科学分野:
- 進化生物学
- ゲノミクス
- 比較ゲノミクス
背景:
- 動物 (メタゾア) と真菌は,共通のエウカリオット超群であるオピストホコンタを共有しています.
- 共通の祖先にもかかわらず 根本的に異なる形状と生活様式を示しています
研究 の 目的:
- オピストホコンタからメタゾアと真菌の分岐に伴う遺伝的変化を再構築する.
- 動物と真菌の進化の軌道を 理解する
主な方法:
- 4つの新しいゲノムを含むデータセットを使用した比較ゲノム分析.
- オピストホコンタの分岐以来の遺伝的変化の再構築.
主要な成果:
- 動物の進化は,メタゾーン以前の祖先から始まって,多細胞性のための遺伝子の蓄積を伴う.
- 菌類の祖先は遺伝子の損失を経験し,より多くの祖先の代謝遺伝子を保持しました.
- メタゾアは遺伝子の融合を多く示し,真菌と原生体は水平遺伝子の移転をより頻繁に利用する.
結論:
- 動物と真菌は,その起源より前の 異なった遺伝的進化の経路に従った.
- 異なるゲノム的な文脈はメタゾアと真菌の出現を容易にした.
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