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Updated: Aug 31, 2025

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
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AAA+ ATPアゼ媒介によるRuvAB-ホリデー結合分岐のメカニズム

Jiri Wald1,2,3,4,5, Dirk Fahrenkamp6,7,8, Nikolaus Goessweiner-Mohr9,10,11,12,13,14

  • 1Institute of Structural and Systems Biology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany. jiri.wald@cssb-hamburg.de.

Nature
|August 24, 2022
PubMed
まとめ

研究者はRuvAB複合体を研究することでDNA再結合のメカニズムを明らかにした. RuvBモータがDNA修復の際にATPの水解をどのように利用するか,時間的に解明された冷凍-EM構造が示しています.

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