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Updated: Aug 31, 2025

Substrate Generation for Endonucleases of CRISPR/Cas Systems
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CraspaseはCRISPRRNA誘導によるRNA活性化プロテアゼである

Chunyi Hu1, Sam P B van Beljouw2,3, Ki Hyun Nam4

  • 1Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA.

Science (New York, N.Y.)
|August 25, 2022
PubMed
まとめ

CRISPR誘導のカスパース (Craspase) は,標的RNA結合によって活性化され,Csx30に対するプロテアースの活性化を可能にします. この自己調節システムは,標的RNAの分裂後にプロテアゼ機能を停止します.

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