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関連する概念動画

Somatosensation01:33

Somatosensation

38.2K
The somatosensory system relays sensory information from the skin, mucous membranes, limbs, and joints. Somatosensation is more familiarly known as the sense of touch. A typical somatosensory pathway includes three types of long neurons: primary, secondary, and tertiary. Primary neurons have cell bodies located near the spinal cord in groups of neurons called dorsal root ganglia. The sensory neurons of ganglia innervate designated areas of skin called dermatomes.
38.2K
Major Somatic Sensory Pathways01:28

Major Somatic Sensory Pathways

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Sensory impulses related to touch, pressure, vibration, and proprioception from various body parts, such as the limbs, trunk, neck, and posterior head, travel to the cerebral cortex through the posterior column-medial lemniscus pathway. The pathway’s name derives from the two white-matter tracts that convey the impulses: the spinal cord's posterior column and the brainstem's medial lemniscus. First-order sensory neurons extend their axons into the spinal cord, forming the...
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Brainstem: Control Centers of Medulla01:21

Brainstem: Control Centers of Medulla

2.1K
The medulla oblongata is a crucial part of the brainstem responsible for controlling various autonomic and involuntary functions. It contains several nuclei, including the olivary, cuneate, gracile, and solitary nuclei.
Olivary Nucleus
The olivary nucleus, or inferior olivary nucleus, is located within the ventrolateral part of the medulla oblongata. It is primarily involved in motor coordination and motor learning. The olivary nucleus receives input from the spinal cord, cerebellum, and motor...
2.1K
Overview of Somatic Sensory Pathways01:29

Overview of Somatic Sensory Pathways

5.2K
Somatic sensory or somatosensory pathways refer to the neural pathways that carry information related to touch, pressure, pain, temperature, and proprioception from the skin, muscles, tendons, and joints to the brain. These pathways involve several stages of processing and integration of sensory information.
The somatosensory system is divided into three main pathways: the dorsal (or posterior) column-medial lemniscus, spinothalamic (or anterolateral), and spinocerebellar pathways.
The dorsal...
5.2K
Brainstem01:19

Brainstem

2.9K
The brainstem, located inferior to the brain and superior to the spinal cord, serves as a bridge between the cerebrum and the spinal cord. It plays a vital role in relaying information and controlling critical life functions. It comprises three primary regions: the midbrain, pons, and medulla oblongata.
The Midbrain
The midbrain is located beneath the diencephalon and connects the cerebrum with the lower parts of the brain. The cerebral peduncles are prominent midbrain structures that house the...
2.9K
Sensory Perception: Organization of the Somatosensory System01:11

Sensory Perception: Organization of the Somatosensory System

4.7K
The somatosensory system is the central and peripheral nervous system component that senses and processes touch, pressure, pain, temperature, and body position or proprioception. The process of sensation takes place at three levels:
The receptor level:
The receptor level is the first stage of sensation. It involves the detection of a stimulus by specialized sensory receptors. The stimulus must arrive within the receptor's receptive field. Next, the receptor converts the energy of the...
4.7K

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Functional Neuroimaging Using Ultrasonic Blood-brain Barrier Disruption and Manganese-enhanced MRI
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Functional Neuroimaging Using Ultrasonic Blood-brain Barrier Disruption and Manganese-enhanced MRI

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内臓感覚のための脳幹の地図

Chen Ran1, Jack C Boettcher1, Judith A Kaye1

  • 1Department of Cell Biology, Howard Hughes Medical Institute, Harvard Medical School, Boston, MA, USA.

Nature
|August 31, 2022
PubMed
まとめ
この要約は機械生成です。

研究 者 たち は,脳幹 の 内臓 の 表現 を マップ し まし た

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科学分野:

  • 神経科学
  • 内部感覚処理

背景:

  • インターオセプティブ感覚処理の原理は 外部感覚システムよりも理解が少ない.
  • 独身管 (NTS) の核は,内臓情報のための重要な脳幹リレーです.

研究 の 目的:

  • 脳が内部臓器の信号を どう表現するか調べるためだ
  • NTSにおける感覚処理の仕組みを理解する.

主な方法:

  • 2フォトンのカルシウムイメージング製剤を開発した
  • NTSニューロンの腸内および上部呼吸道刺激に対する反応を研究した.

主要な成果:

  • 個々のNTSニューロンは 特定の臓器に調整され トポグラフィー的に組織されています
  • 同じ臓器からのメカノセンサリーとケミオセンサリー入力が 集中する
  • 脳幹の抑制は NTSで内臓の表現を鋭くする

結論:

  • NTSは様々な臓器の空間表現を形成しています.
  • 神経阻害は 感覚情報を整理する上で 重要な役割を果たします